HTR6 and MAP1B

Number of citations of the paper that reports this interaction (PubMedID 24614691)
7

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HTR6	MAP1B
Description		5-hydroxytryptamine receptor 6	microtubule associated protein 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse	Photoreceptor Outer Segment Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Cell Junction Axon Dendrite Growth Cone Somatodendritic Compartment Cell Projection Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber
	Molecular Function	G Protein-coupled Receptor Activity Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Tubulin Binding Protein-containing Complex Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Axonogenesis Synapse Assembly Response To Mechanical Stimulus Response To Carbohydrate Cellular Process Response To Inorganic Substance Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Response To Drug Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus
Pathways		Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Nortriptyline Amoxapine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Dimethyltryptamine Lysergic Acid Diethylamide Iloperidone SGS518 Sertindole Mianserin Asenapine Setiptiline Tiapride
Diseases
GWAS		Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)	Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		6 interacting genes: COPS5 FYN GNAQ GNAS MAP1B NF1	29 interacting genes: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D F2RL1 FOS GABRR1 GABRR2 GAN GSK3B HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2
Entrez ID		3362	4131
HPRD ID		03066	01139
Ensembl ID		ENSG00000158748	ENSG00000131711
Uniprot IDs		P50406	A2BDK6 P46821 Q6PJD3 Q86X89
PDB IDs
Enriched GO Terms of Interacting Partners?
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