DNAJA1 and NELFCD

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAJA1	NELFCD
Description		DnaJ heat shock protein family (Hsp40) member A1	negative elongation factor complex member C/D
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GO Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cytoplasmic Side Of Endoplasmic Reticulum Membrane	Nucleoplasm Membrane NELF Complex
	Molecular Function	G Protein-coupled Receptor Binding ATPase Activator Activity Protein Binding ATP Binding Hsp70 Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Chaperone Binding C3HC4-type RING Finger Domain Binding	RNA Binding Protein Binding
	Biological Process	Protein Folding Response To Unfolded Protein Response To Heat Negative Regulation Of Protein Ubiquitination Positive Regulation Of ATPase Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity Regulation Of Protein Transport Protein Localization To Mitochondrion Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR)	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252) Platelet distribution width ( 27863252)
Interacting Genes		22 interacting genes: ARL4D BCS1L BRCA1 CAV2 CD58 CDC16 CFTR ERG FZR1 HIVEP1 HMGCL HSPA8 LSM2 NELFCD NUDT3 PAXIP1 PGR PTEN PTTG1 SUMO4 TM4SF1 TXN	19 interacting genes: AAMP AR ARAF ARPC4 CACNA1A DNAJA1 ENDOV EPRS1 FRMD5 GSTM4 HDAC11 MTA1 NELFA PRMT5 SERF2 SMAD4 TXK UBE3A ZNF638
Entrez ID		3301	51497
HPRD ID		04159	16096
Ensembl ID		ENSG00000086061	ENSG00000101158
Uniprot IDs		B7Z5C0 P31689	H0UI80 Q8IXH7
PDB IDs		2LO1 2M6Y 6E8M	5L3X 6GML
Enriched GO Terms of Interacting Partners?
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