HSD17B4 and MAPK8

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

HSD17B4

MAPK8

Description hydroxysteroid 17-beta dehydrogenase 4 mitogen-activated protein kinase 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • JT interval (sulfonylurea treatment interaction) ( 27958378)
  • Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)
  • QT interval (sulfonylurea treatment interaction) ( 27958378)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Waist-hip ratio ( 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Daytime sleep phenotypes ( 27126917)
Interacting Genes 7 interacting genes: ACTB BAK1 CASP9 CDK7 MAPK8 NDRG1 SNCA 136 interacting genes: AIMP1 AKT1 APBB2 APLP2 APP ATF2 BAD BCL2 BCL2L1 BCL2L11 BMF BMPR2 CAMP CASP3 CBL CCDC88C CDKN1A CDKN2A CDKN2C CEBPA COPS2 CRK CTNNB1 DUSP1 DUSP10 DUSP16 DUSP22 DUSP4 DUSP7 EEF2K EGFR ELK1 ELK3 ELK4 ELP1 EP300 ETV1 FAM193B FZR1 GANAB GARS1 GEMIN5 GFPT1 GORASP2 GSTP1 GUCY1A1 HDAC9 HIVEP1 HRAS HSD17B4 HSF1 HSF4 HSPA8 ID2 IL27RA IRAK1 IRF3 IRS1 ITCH JDP2 JKAMP JUN JUNB JUND KRT8 MAP1B MAP2K1 MAP2K2 MAP2K4 MAP2K7 MAP3K2 MAP3K7 MAPK1 MAPK14 MAPK3 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAP1 MAPKBP1 MAPT MBP MKNK2 MYC NCOA3 NFATC3 NFATC4 NFE2 NKAPD1 NR3C1 NR4A1 PAX2 PDPK1 PIAS2 PIK3R1 PKMYT1 PNRC1 PPARG PRKD1 PRKDC PXN RAD18 RAF1 RASSF1 RBM15 REL RET RPLP2 RPS6KB1 SCAND1 SCOC SERPINB3 SERPINB4 SH3BP5 SHC1 SIRT1 SMAD2 SMAD3 SNCG SP1 SPAG9 SPI1 SPIB SSU72 STAT3 TFCP2 TNFSF11 TP53 TP73 TRAF6 WDR62 WWOX XRCC6 YWHAZ ZNF219 ZNF605
Entrez ID 3295 5599
HPRD ID 03514 03100
Ensembl ID ENSG00000133835 ENSG00000107643
Uniprot IDs A0A0S2Z4J1 B2R659 B3KSP2 E7EWE5 G5E9S2 P51659 A1L4K2 P45983
PDB IDs 1IKT 1S9C 1ZBQ 1UKH 1UKI 2G01 2GMX 2H96 2NO3 2XRW 2XS0 3ELJ 3O17 3O2M 3PZE 3V3V 3VUD 3VUG 3VUH 3VUI 3VUK 3VUL 3VUM 4AWI 4E73 4G1W 4HYS 4HYU 4IZY 4L7F 4QTD 4UX9 4YR8 5LW1 6F5E
Enriched GO Terms of Interacting Partners?
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