AGFG1 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		AGFG1	DNAJC5
Description		ArfGAP with FG repeats 1	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Nuclear Pore Cytosol Cytoplasmic Vesicle Cell Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	DNA Binding RNA Binding GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Acrosome Assembly MRNA Export From Nucleus Multicellular Organism Development Spermatid Nucleus Differentiation Positive Regulation Of GTPase Activity Intermediate Filament Organization Membrane Organization	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Mild influenza (H1N1) infection ( 26379185)	Prostate cancer ( 23535732)
Interacting Genes		13 interacting genes: APC APP DNAJC5 EPS15 EPS15L1 ITSN1 MFHAS1 NYAP2 PKIA POLE2 RNF216 VAMP7 XPO1	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		3267	80331
HPRD ID		02918	08539
Ensembl ID		ENSG00000173744	ENSG00000101152
Uniprot IDs		A0A0S2Z3Y3 A0A0S2Z3Z1 A0A0S2Z444 A0A0S2Z462 P52594	Q6AHX3 Q9H3Z4
PDB IDs		2D9L 2OLM 2VX8	2N04 2N05
Enriched GO Terms of Interacting Partners?
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