HOXC9 and CBX6

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXC9	CBX6
Description		homeobox C9	chromobox 6
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Aggresome	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Single-stranded RNA Binding Protein Binding
	Biological Process	Transcription, DNA-templated Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways			Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bladder cancer ( 24163127 20972438)
Interacting Genes		16 interacting genes: CBX6 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 LPXN NMI PCGF2 POLR2D POLR3D POU2F1 ZFP36 ZNF384	6 interacting genes: HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6
Entrez ID		3225	23466
HPRD ID		00857	13005
Ensembl ID		ENSG00000180806	ENSG00000183741
Uniprot IDs		A0A024RAZ6 P31274	B0QXZ6 O95503
PDB IDs		2LP0 2MSY	3GV6 3I90
Enriched GO Terms of Interacting Partners?
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