APBA1 and ARF3

Number of citations of the paper that reports this interaction (PubMedID 12842896)
38

Data Source:
BioGRID (two hybrid)

		APBA1	ARF3
Description		amyloid beta precursor protein binding family A member 1	ADP ribosylation factor 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Dendritic Spine Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Golgi Membrane Cytoplasm Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Amyloid-beta Binding Protein Binding	GTPase Activity GTP Binding
	Biological Process	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Neurotransmitter Secretion Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Exocytosis	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle-mediated Transport
Pathways		Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors	Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695)	Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Interacting Genes		17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1	14 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 GGA1 GGA2 GGA3 GORAB KIF23 PICK1 SCYL1 SLC2A4
Entrez ID		320	377
HPRD ID		03879	00056
Ensembl ID		ENSG00000107282	ENSG00000134287
Uniprot IDs		Q02410	A0A024R0Y6 P61204
PDB IDs		1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N	6II6
Enriched GO Terms of Interacting Partners?
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