HOXA2 and RALA

		HOXA2	RALA
Description		homeobox A2	RAS like proto-oncogene A
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Determination Osteoblast Development Segment Specification Motor Neuron Axon Guidance Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Rhombomere 2 Development Rhombomere 3 Morphogenesis Brain Segmentation Middle Ear Morphogenesis Negative Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Viscerocranium Morphogenesis Cellular Response To Retinoic Acid	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis Regulation of expression of SLITs and ROBOs	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Chronic venous disease ( 28374850) Tonsillectomy ( 27182965 28928442)
Interacting Genes		5 interacting genes: DMPK MEIS1 NDE1 RALA RCHY1	36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		3199	5898
HPRD ID		05252	01549
Ensembl ID		ENSG00000105996	ENSG00000006451
Uniprot IDs		O43364	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?
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