ANXA11 and ALG2

Number of citations of the paper that reports this interaction (PubMedID 11883939)
19

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		ANXA11	ALG2
Description		annexin A11	ALG2 alpha-1,3/1,6-mannosyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Membrane Midbody Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Actin Cytoskeleton Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding MHC Class II Protein Complex Binding S100 Protein Binding Calcium-dependent Protein Binding	Alpha-1,3-mannosyltransferase Activity GDP-Man:Man1GlcNAc2-PP-Dol Alpha-1,3-mannosyltransferase Activity Protein Binding Protein Heterodimerization Activity Protein N-terminus Binding Calcium-dependent Protein Binding GDP-Man:Man2GlcNAc2-PP-dolichol Alpha-1,6-mannosyltransferase Activity
	Biological Process	Phagocytosis Cytokinetic Process Response To Calcium Ion	Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide-lipid Intermediate Biosynthetic Process Protein Glycosylation In Endoplasmic Reticulum Response To Calcium Ion Mannosylation
Pathways			Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG2 causes ALG2-CDG (CDG-1i)
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Diabetic kidney disease ( 26305897) Sarcoidosis ( 22936702) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		11 interacting genes: ALG2 CEP55 ENO2 EWSR1 HNRNPH3 PDCD6 PLSCR1 S100A6 SRI TFG ZDHHC17	4 interacting genes: ANXA11 PEF1 PTPN23 SRI
Entrez ID		311	85365
HPRD ID		03983	09716
Ensembl ID		ENSG00000122359	ENSG00000119523
Uniprot IDs		P50995 Q5T0G8	A0A024R184 Q9H553
PDB IDs
Enriched GO Terms of Interacting Partners?
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