KCNIP1 and KCND3

Number of citations of the paper that reports this interaction (PubMedID 17187064)
69

Data Source:
BioGRID (pull down)

		KCNIP1	KCND3
Description		potassium voltage-gated channel interacting protein 1	potassium voltage-gated channel subfamily D member 3
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Dendrite Sarcolemma Neuronal Cell Body GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Protein Binding Ion Channel Binding Metal Ion Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Cardiac Conduction Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization
Pathways		Phase 1 - inactivation of fast Na+ channels	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Disopyramide Amitriptyline Imipramine Vernakalant Dalfampridine
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Atrial fibrillation ( 28416822 30061737 29892015) Early cardiac repolarization ( 31600170 22683750) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Medication use (opioids) ( 31015401) Multisite chronic pain ( 31194737) P wave duration ( 24850809) P wave terminal force ( 28794112) PR interval ( 30679814) Response to radiotherapy in cancer (late toxicity) ( 24785509) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		5 interacting genes: KCND1 KCND2 KCND3 KCNIP2 SPP1	2 interacting genes: KCNIP1 KCNIP2
Entrez ID		30820	3752
HPRD ID		06879	16104
Ensembl ID		ENSG00000182132	ENSG00000171385
Uniprot IDs		Q9NZI2	A0A024R0C6 Q9UK17
PDB IDs		1S1E 2I2R 2NZ0	1S1G 2NZ0
Enriched GO Terms of Interacting Partners?
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