HCFC1 and GABPB1

Number of citations of the paper that reports this interaction (PubMedID 10675337)
33

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		HCFC1	GABPB1
Description		host cell factor C1	GA binding protein transcription factor subunit beta 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm Membrane Axon Dendrite Protein-containing Complex Neuronal Cell Body Set1C/COMPASS Complex SAGA-type Complex MLL1 Complex	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Protein Binding, Bridging Activating Transcription Factor Binding Identical Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Cadherin Binding Histone Acetyltransferase Activity (H4-K16 Specific)	DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Hatching Chromatin Remodeling Regulation Of Transcription, DNA-templated Mitochondrion Organization Cell Cycle Positive Regulation Of Gene Expression Protein Deubiquitination Release From Viral Latency Regulation Of Protein Complex Assembly Histone H4 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Protein Stabilization Cellular Response To Organic Cyclic Compound	Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcriptional activation of mitochondrial biogenesis HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338)	Superior frontal gyrus volume ( 31530798)
Interacting Genes		32 interacting genes: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 FOXK2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIN3A SP1 TAF9 THAP11 THAP7 YY1 ZBTB17	24 interacting genes: ADGRB2 ATF1 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 POGZ RBM11 RSPH14 RYBP SLC27A2 SNRPA SNRPB2 TDRD7 TRAF2 USO1 YAF2 ZDHHC17
Entrez ID		3054	2553
HPRD ID		02061	15975
Ensembl ID		ENSG00000172534	ENSG00000104064
Uniprot IDs		A6NEM2 P51610	A0A024R5R5 A0A024R5X6 Q06547
PDB IDs		4GO6 4N39 4N3A 4N3B 4N3C 5LWV 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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