SCHIP1 and TMSB4X

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		SCHIP1	TMSB4X
Description		schwannomin interacting protein 1	thymosin beta 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Cell Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Actin Monomer Binding Protein Binding Enzyme Binding
	Biological Process		Platelet Degranulation Actin Filament Organization Cytoplasmic Sequestering Of NF-kappaB Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Tumor Necrosis Factor-mediated Signaling Pathway Sequestering Of Actin Monomers Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Inflammatory Response Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Interleukin-8 Secretion Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Celiac disease ( 22057235 25920553 18311140) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Iron status biomarkers (total iron binding capacity) ( 28334935) Limited cutaneous systemic scleroderma ( 24387989) Major depressive disorder ( 23377640) Primary biliary cholangitis ( 26394269) Quantitative traits ( 19197348) Self-reported childhood asthma in adult smokers ( 30373671) Systemic sclerosis ( 24387989) Upper eyelid morphology ( 29921221)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		6 interacting genes: FOS NF2 PSMD4 PTMS TMSB4X ZC3H13	29 interacting genes: ACTA1 ACTA2 ACTB ACTG1 ALAS1 ANXA7 APLP1 CDKN1A FAM118B GRB7 IGSF21 ILK KRT13 KRT15 KRT31 KRT40 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6
Entrez ID		29970	7114
HPRD ID		15302	02153
Ensembl ID		ENSG00000151967	ENSG00000205542
Uniprot IDs		P0DPB3	A2VCK8 P62328 Q0P5T0
PDB IDs			1UY5 3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?
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