SEC61A1 and GET3

Number of citations of the paper that reports this interaction (PubMedID 20676083)
113

Data Source:
BioGRID (pull down)

		SEC61A1	GET3
Description		SEC61 translocon subunit alpha 1	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Response To Interferon-gamma Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		9 interacting genes: ACAD9 BAG6 CALM1 GET3 HSPA5 MLH1 SEC61G SERP1 TNF	14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		29927	439
HPRD ID		15316	03555
Ensembl ID		ENSG00000058262	ENSG00000198356
Uniprot IDs		B3KME8 B3KNF6 P61619	O43681
PDB IDs
Enriched GO Terms of Interacting Partners?
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