CARD10 and TMEM43

Number of citations of the paper that reports this interaction (PubMedID 27991920)
7

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology)

		CARD10	TMEM43
Description		caspase recruitment domain family member 10	transmembrane protein 43
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm CBM Complex	Integral Component Of Nuclear Inner Membrane Endoplasmic Reticulum Golgi Apparatus Membrane
	Molecular Function	Protein Binding Receptor Signaling Complex Scaffold Activity CARD Domain Binding	Protein Binding
	Biological Process	Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Apoptotic Process Protein-containing Complex Assembly Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Localization To Nucleus	Nuclear Membrane Organization
Pathways
Drugs
Diseases
GWAS		Autoimmune hepatitis type-1 ( 24768677) Low vWF levels ( 26486471) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc size ( 31809533) Vertical cup-disc ratio ( 25241763 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Heel bone mineral density ( 30598549)
Interacting Genes		6 interacting genes: ATXN7 BCL10 GIPC1 IKBKG KLHL12 TMEM43	5 interacting genes: CARD10 FDFT1 GRAMD2B LMNA SIAH1
Entrez ID		29775	79188
HPRD ID		06233	15541
Ensembl ID		ENSG00000100065	ENSG00000170876
Uniprot IDs		Q9BWT7	A0A024R2F9 Q9BTV4
PDB IDs
Enriched GO Terms of Interacting Partners?
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