BRF1 and GTF3C3

Number of citations of the paper that reports this interaction (PubMedID 10373544)
27

Data Source:
HPRD (in vitro, in vivo)

		BRF1	GTF3C3
Description		BRF1 RNA polymerase III transcription initiation factor subunit	general transcription factor IIIC subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding Transcription Factor Binding TBP-class Protein Binding Metal Ion Binding	DNA Binding Protein Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Positive Regulation Of Transcription By RNA Polymerase III RNA Polymerase III Preinitiation Complex Assembly	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III RNA Polymerase III Preinitiation Complex Assembly
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Huntington's disease progression ( 28642124) Mean platelet volume ( 22139419 27863252) Platelet count ( 29403010 27863252) Platelet distribution width ( 27863252)
Interacting Genes		16 interacting genes: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 RHOU RLIM TBP TP53 UBC	7 interacting genes: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP
Entrez ID		2972	9330
HPRD ID		05361	11997
Ensembl ID		ENSG00000185024	ENSG00000119041
Uniprot IDs		A0A024R6P8 Q92994 V9HVY2	Q9Y5Q9
PDB IDs
Enriched GO Terms of Interacting Partners?
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