GTF2E1 and TAF6

Number of citations of the paper that reports this interaction (PubMedID 7667268)
26

Data Source:
HPRD (in vitro)

		GTF2E1	TAF6
Description		general transcription factor IIE subunit 1	TATA-box binding protein associated factor 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Transcriptional Preinitiation Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex MLL1 Complex
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding	DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	Transcriptional Open Complex Formation At RNA Polymerase II Promoter Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II	Chromatin Organization DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process SnRNA Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Coronary artery disease ( 29212778)
Interacting Genes		27 interacting genes: APP CBFA2T2 CDK7 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F2 GTF2H1 GTF2H4 IKBKG PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1	23 interacting genes: AHR APP CIITA GTF2E1 H3-4 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9
Entrez ID		2960	6878
HPRD ID		01799	11807
Ensembl ID		ENSG00000153767	ENSG00000106290
Uniprot IDs		P29083	A4D299 P49848
PDB IDs		1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L	5FUR 6F3T 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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