BRD7 and H2AC16

Number of citations of the paper that reports this interaction (PubMedID 12489984)
19

Data Source:
HPRD (in vitro)

		BRD7	H2AC16
Description		bromodomain containing 7	H2A clustered histone 16
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleosome Nuclear Chromatin Nucleus Extracellular Exosome
	Molecular Function	P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Histone Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	DNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Cycle Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Positive Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Chromatin Organization Chromatin Silencing Biological_process
Pathways		Regulation of TP53 Activity through Acetylation	HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS		Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4-16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PCBD1 PSMD11 PTPN13 RBFOX2 RIF1 RPLP1 SERPINB9 TP53 TRIM24	5 interacting genes: BRD7 CRP GADD45A SAP30 TERF2IP
Entrez ID		29117	8332
HPRD ID		12531	09103
Ensembl ID		ENSG00000166164	ENSG00000276903
Uniprot IDs		Q9NPI1	A4FTV9 P0C0S8
PDB IDs		2I7K 5MQ1	4QYL 5KGF 6R0C 6RNY
Enriched GO Terms of Interacting Partners?
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