HIPK2 and DDX39A

Number of citations of the paper that reports this interaction (PubMedID 14667819)
35

Data Source:
HPRD (two hybrid)

		HIPK2	DDX39A
Description		homeodomain interacting protein kinase 2	DExD-box helicase 39A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body PML Body RNA Polymerase II Transcription Factor Complex	Transcription Export Complex Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding SMAD Binding Virion Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transforming Growth Factor Beta Receptor Signaling Pathway Smoothened Signaling Pathway Adult Walking Behavior Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Retina Layer Formation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Modulation By Virus Of Host Morphology Or Physiology Neuron Differentiation Erythrocyte Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway PML Body Organization Positive Regulation Of Protein Binding Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of DNA Binding Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade Embryonic Camera-type Eye Morphogenesis Voluntary Musculoskeletal Movement Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Cell Cycle Embryonic Retina Morphogenesis In Camera-type Eye Lens Induction In Camera-type Eye SMAD Protein Signal Transduction Iris Morphogenesis Cellular Response To Hypoxia Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression SUMOylation of transcription cofactors Physiological factors Regulation of TP53 Activity through Phosphorylation RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MECP2 expression and activity	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Systolic blood pressure ( 28135244)
Interacting Genes		54 interacting genes: AATF ABL1 BTRC CBX3 CHMP4B CREBBP CUL1 CXCL1 DAXX DDX39A DDX39B EP300 FBXW7 H2BC21 HMGA1 KAT2B MAP3K7 MBP MDM2 MECP2 MKNK1 MYB MYBL1 NKX2-1 NKX2-5 NKX3-1 NLK PARP1 PAX6 PML PTCH1 RANBP9 RUNX1 SCAP SENP1 SIAH1 SIAH2 SIRT1 SKI SMAD1 SMAD2 SMAD3 SP100 SUMO1 SUMO2 SUMO3 TP53 TP53INP1 TP63 TP73 TRADD UBE2I WSB1 ZBTB4	11 interacting genes: CCL14 DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 SARNP SAT1 TERF1 TERF2IP UBE2I
Entrez ID		28996	10212
HPRD ID		06039	10861
Ensembl ID		ENSG00000064393	ENSG00000123136
Uniprot IDs		Q9H2X6	O00148
PDB IDs		6P5S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?