BZW2 and EIF3A

Number of citations of the paper that reports this interaction (PubMedID 21745818)
16

Data Source:
BioGRID (pull down)

		BZW2	EIF3A
Description		basic leucine zipper and W2 domains 2	eukaryotic translation initiation factor 3 subunit A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Microtubule Postsynaptic Density Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Multi-eIF Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Protein Binding Cadherin Binding	RNA Binding MRNA Binding Translation Initiation Factor Activity Structural Molecule Activity Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	Nervous System Development Cell Differentiation	Formation Of Cytoplasmic Translation Initiation Complex Translation Reinitiation Translational Initiation Negative Regulation Of ERK1 And ERK2 Cascade IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Alcoholic chronic pancreatitis ( 28754779) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
Interacting Genes		6 interacting genes: AGMO AGR3 EIF2A EIF2B1 EIF3A GSK3B	20 interacting genes: BBS1 BBS4 BZW2 CACNA1A EIF3B EIF3G EIF3I EIF3J EIF4B EIF4G1 EIF4G2 MTNR1B PAIP1 REL RNF139 SRPK2 TFIP11 UBC UPF1 YWHAZ
Entrez ID		28969	8661
HPRD ID		16571	03618
Ensembl ID		ENSG00000136261	ENSG00000107581
Uniprot IDs		A0A024RA42 Q9Y6E2	Q14152
PDB IDs			3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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