GPX7 and GET3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		GPX7	GET3
Description		glutathione peroxidase 7	guided entry of tail-anchored proteins factor 3, ATPase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Cellular Response To Oxidative Stress Oxidation-reduction Process Cellular Oxidant Detoxification	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Detoxification of Reactive Oxygen Species	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Glutathione	ATP
Diseases
GWAS		Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		6 interacting genes: CEP70 CPEB2 ERO1A GET3 SGTA UBQLN4	14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		2882	439
HPRD ID		13606	03555
Ensembl ID		ENSG00000116157	ENSG00000198356
Uniprot IDs		Q96SL4	O43681
PDB IDs		2P31
Enriched GO Terms of Interacting Partners?
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