GPS1 and IP6K1

Number of citations of the paper that reports this interaction (PubMedID 25349427)
15

Data Source:
BioGRID (pull down)

		GPS1	IP6K1
Description		G protein pathway suppressor 1	inositol hexakisphosphate kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Fibrillar Center Nucleoplasm Cytosol
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Inositol Hexakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Inositol Hexakisphosphate 1-kinase Activity Inositol Hexakisphosphate 3-kinase Activity
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Inositol Phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Negative Regulation Of Cold-induced Thermogenesis
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	Synthesis of pyrophosphates in the cytosol Synthesis of IPs in the nucleus
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Body mass index ( 26426971) Diastolic blood pressure ( 27841878) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 23128233) Intelligence (MTAG) ( 29326435) Parental longevity (mother's age at death or mother's attained age) ( 31484785) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 29769521 27798624) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 27841878) Ulcerative colitis ( 25082827)
Interacting Genes		21 interacting genes: COPS2 COPS3 COPS5 COPS6 COPS7A COPS8 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53	7 interacting genes: CACNA1A CLK1 COPS2 DDB1 EXOSC7 GPS1 RAB3IL1
Entrez ID		2873	9807
HPRD ID		15991	07379
Ensembl ID		ENSG00000169727	ENSG00000176095
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	A0A024R2X2 Q92551
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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