GRK5 and SNCG

Number of citations of the paper that reports this interaction (PubMedID 10852916)
116

Data Source:
BioGRID (enzymatic study)
HPRD (in vitro)

		GRK5	SNCG
Description		G protein-coupled receptor kinase 5	synuclein gamma
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Nuclear Speck Nuclear Membrane	Cytoplasm Centrosome Spindle Nuclear Body Axon Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity G Protein-coupled Receptor Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Phospholipid Binding Beta-adrenergic Receptor Kinase Activity	Protein Binding
	Biological Process	Apoptotic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Proliferation Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Fat Cell Differentiation Protein Autophosphorylation Regulation Of Cell Cycle	Chemical Synaptic Transmission Adult Locomotory Behavior Protein Secretion Regulation Of Dopamine Secretion Regulation Of Neurotransmitter Secretion Synapse Organization
Pathways		G alpha (q) signalling events G alpha (s) signalling events
Drugs
Diseases
GWAS		Coronary artery aneurysm in Kawasaki disease ( 27171184) Early onset periodontitis x smoking status interaction ( 31537151) Height ( 28552196) Mean platelet volume ( 27863252) Methadone dose in opioid dependence ( 30060048) Obesity-related traits ( 23251661) Platelet distribution width ( 27863252) Risky sexual behaviors in alcohol dependence ( 28990359) Type 2 diabetes ( 22961080) Venous thromboembolism ( 31420334 31676865)
Interacting Genes		19 interacting genes: ADRB2 AGTR1 AVPR1A AVPR1B AVPR2 BDKRB2 CABP1 CALM1 CAV1 CHRM2 DLGAP2 GIT1 RCVRN RHO SNCA SNCB SNCG TACR1 TBXA2R	11 interacting genes: ADRB2 BUB1B GRK1 GRK5 GRK6 MAPK1 MAPK3 MAPK8 POT1 TERF1 TERF2IP
Entrez ID		2869	6623
HPRD ID		02926	04297
Ensembl ID		ENSG00000198873	ENSG00000173267
Uniprot IDs		P34947	F8W754 O76070 Q6FHG5
PDB IDs		4TNB 4TND
Enriched GO Terms of Interacting Partners?
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