GPR37 and SYVN1

Number of citations of the paper that reports this interaction (PubMedID 15572843)
0

Data Source:
BioGRID (enzymatic study)

		GPR37	SYVN1
Description		G protein-coupled receptor 37	synoviolin 1
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Hrd1p Ubiquitin Ligase Complex Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding	Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding ATPase Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol IRE1-mediated Unfolded Protein Response ERAD Pathway Protein Stabilization Protein K48-linked Ubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Mannose Trimming
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	XBP1(S) activates chaperone genes Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 26237428) Reading and spelling ( 23738518)	Blood protein levels ( 28240269)
Interacting Genes		9 interacting genes: ADRB2 GABARAPL2 GLP1R GRIP1 HSPA1A PRKN SDCBP STUB1 SYVN1	13 interacting genes: APP ATN1 ATP6AP1 CLU ERN1 GPR37 TP53 UBE2D2 UBE2D3 UBE2G1 UBE2U UBE2Z USP7
Entrez ID		2861	84447
HPRD ID		03992	07618
Ensembl ID		ENSG00000170775	ENSG00000162298
Uniprot IDs		O15354	Q86TM6
PDB IDs			6A3Z
Enriched GO Terms of Interacting Partners?
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