GOT2 and GLRX

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		GOT2	GLRX
Description		glutamic-oxaloacetic transaminase 2	glutaredoxin
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface T-tubule Protein-containing Complex Perikaryon Extracellular Exosome	Cell Nucleus Cytosol Extracellular Exosome
	Molecular Function	RNA Binding L-aspartate:2-oxoglutarate Aminotransferase Activity Phospholipid Binding Kynurenine-oxoglutarate Transaminase Activity Amino Acid Binding Enzyme Binding Pyridoxal Phosphate Binding Identical Protein Binding	Electron Transfer Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Gluconeogenesis 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Aspartate Metabolic Process Aspartate Biosynthetic Process Aspartate Catabolic Process Glutamate Metabolic Process Female Pregnancy Lactation Cellular Amino Acid Biosynthetic Process Response To Muscle Activity Fatty Acid Transport 4-hydroxyproline Catabolic Process Glutamate Catabolic Process To Aspartate Glutamate Catabolic Process To 2-oxoglutarate Response To Insulin Response To Morphine Response To Ethanol Glyoxylate Metabolic Process L-kynurenine Metabolic Process	Nucleobase-containing Small Molecule Interconversion Electron Transport Chain Cell Redox Homeostasis Positive Regulation Of Membrane Potential Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Degradation of cysteine and homocysteine Glyoxylate metabolism and glycine degradation Gluconeogenesis Aspartate and asparagine metabolism Glutamate and glutamine metabolism	Interconversion of nucleotide di- and triphosphates
Drugs		Pyridoxal Phosphate L-Aspartic Acid Glutamic Acid 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate	Glutathione
Diseases
GWAS		Aortic root size ( 21223598) Aspartate aminotransferase levels ( 29403010) Automobile speeding propensity ( 30643258) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Impulsivity (attentional) ( 30718321) Metabolite levels ( 23823483) QT interval ( 19305408) Urinary metabolite levels in chronic kidney disease ( 31959995) Uterine fibroid number (single vs multiple) ( 30196971)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		11 interacting genes: APCS CCL21 CSNK2A2 GAPDH GLRX GLUD1 HSPA8 MDH2 PC THOC7 ZDHHC6	7 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1
Entrez ID		2806	2745
HPRD ID		00684	02707
Ensembl ID		ENSG00000125166	ENSG00000173221
Uniprot IDs		P00505	A0A024RAM2 P35754
PDB IDs		5AX8	1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?