GNRH1 and GNRHR

Number of citations of the paper that reports this interaction (PubMedID 9414473)
3

Data Source:
HPRD (in vivo)

		GNRH1	GNRHR
Description		gonadotropin releasing hormone 1	gonadotropin releasing hormone receptor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Mitochondrion Golgi-associated Vesicle Dendrite Perikaryon Axon Terminus Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane Neurosecretory Vesicle	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Hormone Activity Gonadotropin Hormone-releasing Hormone Activity Gonadotropin-releasing Hormone Receptor Binding	G Protein-coupled Receptor Activity Gonadotropin-releasing Hormone Receptor Activity Peptide Binding
	Biological Process	Reproduction Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Female Pregnancy Aging Negative Regulation Of Cell Proliferation Regulation Of Gene Expression Male Sex Determination Response To Corticosteroid Response To Lipopolysaccharide Negative Regulation Of Immature T Cell Proliferation Response To Testosterone Response To Prostaglandin E Response To Potassium Ion Negative Regulation Of Apoptotic Process Estrous Cycle Response To Ethanol Response To Prolactin Regulation Of Ovarian Follicle Development Negative Regulation Of Neuron Migration	G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Cellular Response To Hormone Stimulus Cellular Response To Gonadotropin-releasing Hormone
Pathways		Hormone ligand-binding receptors G alpha (q) signalling events	Hormone ligand-binding receptors G alpha (q) signalling events
Drugs			Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Degarelix Buserelin Ganirelix Histrelin Triptorelin Elagolix
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Heel bone mineral density ( 30598549) Length of menstrual cycle ( 30202859) Menopause (age at onset) ( 29773799) Metabolite levels ( 23823483)	Regular attendance at a pub or social club ( 29970889)
Interacting Genes		2 interacting genes: GNRHR MEP1A	2 interacting genes: GNRH1 RGS10
Entrez ID		2796	2798
HPRD ID		08860	00732
Ensembl ID		ENSG00000147437	ENSG00000109163
Uniprot IDs		P01148	P30968
PDB IDs		4D5M
Enriched GO Terms of Interacting Partners?
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