MAT2B and MAT2A

Number of citations of the paper that reports this interaction (PubMedID 12671891)
33

Data Source:
HPRD (in vivo)

		MAT2B	MAT2A
Description		methionine adenosyltransferase 2B	methionine adenosyltransferase 2A
Image
GO Annotations	Cellular Component	Nucleus Cytosol Methionine Adenosyltransferase Complex Extracellular Exosome	Cytosol Methionine Adenosyltransferase Complex
	Molecular Function	Protein Binding Enzyme Binding Methionine Adenosyltransferase Regulator Activity	Methionine Adenosyltransferase Activity Protein Binding ATP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Methylation Regulation Of Catalytic Activity	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Methylation Protein Hexamerization Protein Heterooligomerization Cellular Response To Leukemia Inhibitory Factor
Pathways		Methylation Ub-specific processing proteases	Methylation
Drugs			Ademetionine
Diseases
GWAS		Aging ( 22773346) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Broad depression or major depressive disorder (self-reported) ( 30626913) Chronotype ( 30696823) Common carotid intima-media thickness ( 29206233) General risk tolerance (MTAG) ( 30643258) Methadone dose in opioid dependence ( 28115739) Neuritic plaque ( 31497858) Number of sexual partners ( 30643258) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Smoking initiation ( 24665060) Uterine fibroid size (maximum dimension) ( 30196971) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)	Coronary artery disease ( 29212778 30104761) Dysmenorrheic pain ( 27454463) Urinary albumin excretion ( 30220432)
Interacting Genes		12 interacting genes: APP CNIH4 FBXO25 GABRA1 KPNA3 KPNA4 MAT2A MSX2 STC1 TMED9 TRIM27 YTHDF3	5 interacting genes: CUL3 HGS MAT2B TMEM213 UBE2I
Entrez ID		27430	4144
HPRD ID		05701	03275
Ensembl ID		ENSG00000038274	ENSG00000168906
Uniprot IDs		A0A140VJP2 Q9NZL9	A0A140VJP5 P31153
PDB IDs		2YDX 2YDY 4KTT 4KTV 4NDN	2P02 4KTT 4KTV 4NDN 5A19 5A1G 5A1I 5UGH 6FAJ 6FBN 6FBO 6FBP 6FCB 6FCD 6FWB 6G6R
Enriched GO Terms of Interacting Partners?
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