AFF4 and MLLT1

Number of citations of the paper that reports this interaction (PubMedID 26344197)
117

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (two hybrid)

		AFF4	MLLT1
Description		AF4/FMR2 family member 4	MLLT1 super elongation complex subunit
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Elongation Factor Complex ELL-EAF Complex Transcriptionally Active Chromatin	Fibrillar Center Nucleus Nucleoplasm Cytosol Transcription Elongation Factor Complex
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Spermatid Development Regulation Of Gene Expression	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Asthma ( 31619474) Estimated glomerular filtration rate ( 31152163) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)
Interacting Genes		10 interacting genes: AP2B1 CCNT1 CDK9 GOLGA2 LRRK2 MLLT1 MTUS2 SIAH1 SPP1 TRAF2	11 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 H1-5 H3-4 MLLT10 PAF1 WDR5
Entrez ID		27125	4298
HPRD ID		09187	15933
Ensembl ID		ENSG00000072364	ENSG00000130382
Uniprot IDs		Q9UHB7	Q03111
PDB IDs		4IMY 4OGR 4OR5 5JW9 5L1Z 6CYT 6R80	5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O
Enriched GO Terms of Interacting Partners?
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