GJA5 and RIMS3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GJA5	RIMS3
Description		gap junction protein alpha 5	regulating synaptic membrane exocytosis 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Gap Junction Connexin Complex Intercalated Disc Cell Projection	Cell Junction Presynaptic Membrane Synapse Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component
	Molecular Function	Gap Junction Hemi-channel Activity Connexin Binding Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Disordered Domain Specific Binding	Rab GTPase Binding Ion Channel Binding
	Biological Process	Skeletal System Development Angiogenesis Negative Regulation Of Glomerular Filtration Outflow Tract Morphogenesis Endothelium Development Cardiac Conduction System Development Mitral Valve Development Pulmonary Valve Formation Ventricular Septum Development Atrial Septum Development Septum Primum Development Atrial Ventricular Junction Remodeling Potassium Ion Transport Cell Communication By Chemical Coupling Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Gap Junction Assembly Embryonic Limb Morphogenesis Embryonic Heart Tube Development Foramen Ovale Closure Negative Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Artery Morphogenesis Transmembrane Transport Regulation Of Cardiac Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Ventricular Septum Morphogenesis Atrial Septum Morphogenesis Ventricular Cardiac Muscle Cell Action Potential SA Node Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Blood Vessel Diameter Regulation Of AV Node Cell Action Potential Regulation Of Bundle Of His Cell Action Potential Regulation Of Purkinje Myocyte Action Potential Regulation Of Atrial Cardiac Muscle Cell Action Potential Regulation Of Renin Secretion Into Blood Stream Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vasomotion	Calcium Ion Regulated Exocytosis Regulation Of Membrane Potential Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Exocytosis
Pathways		Gap junction assembly
Drugs
Diseases		Atrial fibrillation
GWAS		Atrial fibrillation ( 30061737 29892015) Cognitive performance ( 20125193) Methotrexate-induced interstitial lung disease in rheumatoid arthritis ( 28500057)
Interacting Genes		6 interacting genes: AAR2 GJA1 MARK1 PRKACA RIMS3 UBQLN4	3 interacting genes: BANP CREB3 GJA5
Entrez ID		2702	9783
HPRD ID		08699	17976
Ensembl ID		ENSG00000265107	ENSG00000117016
Uniprot IDs		P36382 X5D2H9	Q9UJD0
PDB IDs
Enriched GO Terms of Interacting Partners?
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