SEC22A and ERLIN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC22A	ERLIN1
Description		SEC22 homolog A, vesicle trafficking protein	ER lipid raft associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Transporter Activity Protein Binding	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Transport	Cholesterol Metabolic Process Ubiquitin-dependent ERAD Pathway SREBP Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process Transmembrane Transport
Pathways		COPII-mediated vesicle transport	ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Liver enzyme levels ( 18940312) Response to radiotherapy in cancer (late toxicity) ( 24785509) Squamous cell lung carcinoma ( 28604730) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		11 interacting genes: DTX2 EDA ERLIN1 FATE1 LMNA MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79	4 interacting genes: AGR3 FA2H SEC22A TMEM199
Entrez ID		26984	10613
HPRD ID		15313	08502
Ensembl ID		ENSG00000121542	ENSG00000107566
Uniprot IDs		Q96IW7	O75477
PDB IDs
Enriched GO Terms of Interacting Partners?
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