COPG2 and HES4

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		COPG2	HES4
Description		COPI coat complex subunit gamma 2	hes family bHLH transcription factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone	Nuclear Chromatin Nucleus
	Molecular Function	Structural Molecule Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Transcription Factor Binding Protein Dimerization Activity E-box Binding N-box Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Secretion Organelle Transport Along Microtubule	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Cell Differentiation Negative Regulation Of Neuron Differentiation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10	5 interacting genes: COPG2 LTN1 PCBD1 PCBD2 RGS3
Entrez ID		26958	57801
HPRD ID		05074	16273
Ensembl ID		ENSG00000158623	ENSG00000188290
Uniprot IDs		A0A140VK12 Q9NSM7 Q9UBF2	D6REB3 E9PB28 Q9HCC6
PDB IDs
Enriched GO Terms of Interacting Partners?
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