GHRHR and MLNR

Number of citations of the paper that reports this interaction (PubMedID 12606621)
11

Data Source:
HPRD (in vivo)

		GHRHR	MLNR
Description		growth hormone releasing hormone receptor	motilin receptor
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nuclear Inner Membrane Nuclear Outer Membrane Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Nuclear Matrix Secretory Granule Sarcolemma	Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Growth Hormone-releasing Hormone Receptor Activity Peptide Hormone Binding Growth Factor Binding	G Protein-coupled Peptide Receptor Activity Hormone Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Lactation Positive Regulation Of Cell Proliferation Determination Of Adult Lifespan CAMP-mediated Signaling Water Homeostasis Response To Insulin Cellular Response To Insulin Stimulus Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Multicellular Organism Growth Hormone Metabolic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Estrogen Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Cell Maturation Multicellular Organismal Reproductive Process Regulation Of Protein Metabolic Process Response To Glucocorticoid Positive Regulation Of Growth Hormone Secretion Somatotropin Secreting Cell Development Cellular Response To Glucose Stimulus	G Protein-coupled Receptor Signaling Pathway
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Sermorelin Tesamorelin	Erythromycin
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes		3 interacting genes: GHRH GHRL MLNR	4 interacting genes: GHRHR GHRL GPRASP1 MLN
Entrez ID		2692	2862
HPRD ID		00748	04197
Ensembl ID		ENSG00000106128	ENSG00000102539
Uniprot IDs		A0A090N8Y6 Q02643	O43193
PDB IDs		2XDG
Enriched GO Terms of Interacting Partners?
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