HAVCR1 and DYNLT1

Number of citations of the paper that reports this interaction (PubMedID 29693725)
0

Data Source:
BioGRID (affinity chromatography technology, pull down)

		HAVCR1	DYNLT1
Description		hepatitis A virus cellular receptor 1	dynein light chain Tctex-type 1
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GO Annotations	Cellular Component	Integral Component Of Membrane Motile Cilium	Extracellular Region Cell Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Virus Receptor Activity	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Viral Entry Into Host Cell	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Cholesterol, total ( 25961943 20686565) Hypertriglyceridemia ( 23505323) LDL cholesterol ( 19060906 25961943 20686565) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 29593015) Total cholesterol levels ( 29403010) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 25961943 20686565)
Interacting Genes		3 interacting genes: DYNLT1 SEMA4A UBQLN4	26 interacting genes: APP BAG3 BMPR2 DDX54 DHX33 DOC2A DOC2B DVL1 DVL2 DYNC1I1 FXR2 HAVCR1 HSPB9 ILF2 KIF2A NUP153 NUP62 PVR RAD21 RBM14 SVIL TROAP TUBA3C TXN VDAC1 XRN2
Entrez ID		26762	6993
HPRD ID		09404	15987
Ensembl ID		ENSG00000113249	ENSG00000146425
Uniprot IDs		B4DPB1 E9PFX0 Q96D42	P63172
PDB IDs		5DZO 5F70	5JPW
Enriched GO Terms of Interacting Partners?
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