GAPDHS and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		GAPDHS	SH3BP4
Description		glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	SH3 domain binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding NADP Binding NAD Binding	GDP-dissociation Inhibitor Activity Protein Binding Ras GTPase Binding Identical Protein Binding
	Biological Process	Gluconeogenesis Glycolytic Process Flagellated Sperm Motility Positive Regulation Of Glycolytic Process Canonical Glycolysis	Endocytosis Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		Association of TriC/CCT with target proteins during biosynthesis Glycolysis Gluconeogenesis	Amino acids regulate mTORC1
Drugs		NADH Zinc 6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine Artenimol
Diseases
GWAS		Diastolic blood pressure ( 28234671) Systolic blood pressure ( 28234671)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666)
Interacting Genes		2 interacting genes: APP SH3BP4	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		26330	23677
HPRD ID		13566	09285
Ensembl ID		ENSG00000105679	ENSG00000130147
Uniprot IDs		A0A0K0K1K1 O14556	Q9P0V3
PDB IDs		3H9E 3PFW 5C7L 5C7O
Enriched GO Terms of Interacting Partners?
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