GMEB2 and CBFA2T3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GMEB2	CBFA2T3
Description		glucocorticoid modulatory element binding protein 2	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription	Response To Hypoxia Negative Regulation Of Cell Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Mean corpuscular hemoglobin ( 27863252) Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		7 interacting genes: ATXN1 ATXN1L CBFA2T3 CREBBP GMEB1 PVR UBE2I	15 interacting genes: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 NUP98 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652
Entrez ID		26205	863
HPRD ID		16245	04847
Ensembl ID		ENSG00000101216	ENSG00000129993
Uniprot IDs		B4DQS0 Q9UKD1	O75081
PDB IDs
Enriched GO Terms of Interacting Partners?
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