TRAF3IP1 and SMC4

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		TRAF3IP1	SMC4
Description		TRAF3 interacting protein 1	structural maintenance of chromosomes 4
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GO Annotations	Cellular Component	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base	Condensin Complex Condensin Core Heterodimer Nucleus Nucleoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Microtubule Binding	Single-stranded DNA Binding Protein Binding ATP Binding
	Biological Process	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Protein Complex Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Intraciliary Transport Involved In Cilium Assembly Post-anal Tail Morphogenesis Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning	Mitotic Sister Chromatid Segregation Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization
Pathways		Intraflagellar transport Intraflagellar transport	Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756)
Interacting Genes		28 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC	3 interacting genes: NCAPD2 SMC2 TRAF3IP1
Entrez ID		26146	10051
HPRD ID		09571	09276
Ensembl ID		ENSG00000204104	ENSG00000113810
Uniprot IDs		Q8TDR0	B3KXX5 E9PD53 Q58F29 Q9NTJ3
PDB IDs		2EQO	4U4P
Enriched GO Terms of Interacting Partners?
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