SETBP1 and YAF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SETBP1	YAF2
Description		SET binding protein 1	YY1 associated factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases		Schinzel-Giedion midface retraction syndrome
GWAS		Bone ultrasound measurement (velocity of sound) ( 28472463) Breast cancer ( 25751625 29059683 31757997) Coronary artery aneurysm in Kawasaki disease ( 27171184) Diastolic blood pressure ( 27618452) Estimated glomerular filtration rate ( 31152163) Hair color ( 26926045) Heel bone mineral density ( 30598549) Male-pattern baldness ( 29146897 22693459 28196072) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Number of sexual partners ( 30643258) Platelet thrombus formation ( 22550155) Pulse pressure ( 27841878) QRS duration ( 30679814 27577874 30012220 25035420 27659466) QRS interval (sulfonylurea treatment interaction) ( 27958378) Restless legs syndrome ( 29029846) Systolic blood pressure ( 27841878 28739976 27618452) Waist circumference ( 28552196)
Interacting Genes		12 interacting genes: APP DENND11 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXC SPANXD SUMO1P1 UBE2I XAGE1B YAF2	10 interacting genes: GABPB1 MYC MYCN NEDD8 SETBP1 TBK1 UBC XAGE1B YY1 ZFP42
Entrez ID		26040	10138
HPRD ID		10224	09606
Ensembl ID		ENSG00000152217	ENSG00000015153
Uniprot IDs		Q9Y6X0	B4DJQ9 G3V212 Q8IY57
PDB IDs			2D9G
Enriched GO Terms of Interacting Partners?
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