GAPDH and PRDX1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (biochemical, two hybrid)
HPRD (two hybrid)

		GAPDH	PRDX1
Description		glyceraldehyde-3-phosphate dehydrogenase	peroxiredoxin 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Lipid Droplet Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome GAIT Complex Ribonucleoprotein Complex	Extracellular Space Cell Nucleus Cytoplasm Cytosol Melanosome Extracellular Exosome
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Aspartic-type Endopeptidase Inhibitor Activity Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding Disordered Domain Specific Binding	RNA Binding Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Identical Protein Binding Cadherin Binding
	Biological Process	Microtubule Cytoskeleton Organization Gluconeogenesis Glycolytic Process Negative Regulation Of Endopeptidase Activity Regulation Of Macroautophagy Negative Regulation Of Translation Killing Of Cells Of Other Organism Peptidyl-cysteine S-trans-nitrosylation Positive Regulation Of Cytokine Secretion Protein Stabilization Defense Response To Fungus Neuron Apoptotic Process Killing By Host Of Symbiont Cells Positive Regulation By Organism Of Apoptotic Process In Other Organism Involved In Symbiotic Interaction Canonical Glycolysis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Interferon-gamma	Skeletal System Development Retina Homeostasis Response To Oxidative Stress Cell Proliferation Removal Of Superoxide Radicals Natural Killer Cell Activation Regulation Of Stress-activated MAPK Cascade Cellular Response To Stress Erythrocyte Homeostasis Cellular Response To Oxidative Stress Natural Killer Cell Mediated Cytotoxicity Hydrogen Peroxide Catabolic Process Leukocyte Activation Cell Redox Homeostasis Oxidation-reduction Process Regulation Of NIK/NF-kappaB Signaling
Pathways		Glycolysis Gluconeogenesis	Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		NADH Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Xanthinol Copper	Zinc Copper Artenimol
Diseases
GWAS		Blood protein levels ( 30072576)	Blood protein levels ( 28240269) Body mass index ( 26426971)
Interacting Genes		79 interacting genes: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FBXO7 FKBP6 GADD45A GAS7 GOT2 GRIA2 GRM1 HES1 HNF4G HSPB2 HTT KARS1 KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MTNR1A MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 PTPRF RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	26 interacting genes: ABL1 ADH5 BTRC CALM1 CLEC4G EGFR EXOSC3 GAPDH IRF3 LUC7L MTRNR2L1 MYC MYD88 PPP2R1A PPP2R1B PRDX4 PTEN SESN1 SESN2 SH2D1B SMARCD1 SNCA TERF1 UBE3A VHL YWHAQ
Entrez ID		2597	5052
HPRD ID		00713	01458
Ensembl ID		ENSG00000111640	ENSG00000117450
Uniprot IDs		P04406 V9HVZ4	A0A384NPQ2 Q06830
PDB IDs		1U8F 1ZNQ 2FEH 3GPD 4WNC 4WNI 6ADE 6IQ6	2RII 3HY2 4XCS
Enriched GO Terms of Interacting Partners?
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