GABRG2 and GABRA2

Number of citations of the paper that reports this interaction (PubMedID 31080408)
2

Data Source:
BioGRID (fluorescent resonance energy transfer)

		GABRG2	GABRA2
Description		gamma-aminobutyric acid type A receptor subunit gamma2	gamma-aminobutyric acid type A receptor subunit alpha2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Axon Cytoplasmic Vesicle Membrane Dendrite Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Postsynapse GABA-ergic Synapse GABA-A Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Integral Component Of Synaptic Vesicle Membrane Dendrite Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Postsynapse GABA-A Receptor Complex
	Molecular Function	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Binding Benzodiazepine Receptor Activity GABA-gated Chloride Ion Channel Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Benzodiazepine Receptor Activity GABA-gated Chloride Ion Channel Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Post-embryonic Development Adult Behavior Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Cellular Response To Histamine Chloride Transmembrane Transport Inhibitory Synapse Assembly	Regulation Of Neurotransmitter Levels Neurotransmitter Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport Inhibitory Synapse Assembly
Pathways		Signaling by ERBB4 GABA receptor activation GABA receptor activation	GABA receptor activation GABA receptor activation
Drugs		Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Topiramate Etomidate Talbutal Pentobarbital Olanzapine Clobazam Meprobamate Carisoprodol Eszopiclone Alprazolam Zolpidem Metharbital Chlordiazepoxide Amoxapine Adinazolam Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Triazolam Triazolam Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Flumazenil Flumazenil Estazolam Estazolam Sevoflurane Ginkgo biloba Glutethimide Flunitrazepam Bromazepam Clotiazepam Fludiazepam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Adipiplon Stiripentol Etizolam Thiocolchicoside Muscimol Lormetazepam	Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Butalbital Topiramate Etomidate Talbutal Talbutal Pentobarbital Pentobarbital Olanzapine Clobazam Meprobamate Meprobamate Eszopiclone Eszopiclone Alprazolam Secobarbital Zolpidem Metharbital Metharbital Chlordiazepoxide Amoxapine Adinazolam Thiopental Clorazepate Acamprosate Midazolam Flurazepam Isoflurane Primidone Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Methylphenobarbital Triazolam Triazolam Ethanol Methoxyflurane Ergoloid mesylate Clonazepam Methyprylon Halothane Desflurane Zopiclone Flumazenil Estazolam Estazolam Sevoflurane Quinidine barbiturate Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Glutethimide Barbital Barbituric acid derivative Flunitrazepam Bromazepam Clotiazepam Fludiazepam Prazepam Prazepam Quazepam Quazepam Cinolazepam Nitrazepam Prasterone Taurine Pagoclone Ganaxolone Adipiplon Stiripentol Etizolam Thiocolchicoside Lormetazepam
Diseases		Febrile seizures, including: Febrile convulsions; Generalized epilepsy with febrile seizure plus (GEFS+); Dravet syndrome/ Severe myoclonic epilepsy in infancy (SMEI) Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Cognitive decline rate in late mild cognitive impairment ( 26252872) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Severe influenza A (H1N1) infection ( 26379185)	Adventurousness ( 30643258) Epilepsy ( 25087078) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 30531953) Systolic blood pressure ( 30224653)
Interacting Genes		8 interacting genes: DRD5 GABARAP GABRA2 LARP7 PPP3CA PRKCA PRKCB ZDHHC3	2 interacting genes: GABRG2 UBQLN1
Entrez ID		2566	2555
HPRD ID		00663	11747
Ensembl ID		ENSG00000113327	ENSG00000151834
Uniprot IDs		P18507	A0A024R9X6 E9PBQ7 P47869
PDB IDs		6D6T 6D6U 6HUG 6HUJ 6HUK 6HUO 6HUP 6I53
Enriched GO Terms of Interacting Partners?
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