FTH1 and MYL3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		FTH1	MYL3
Description		ferritin heavy chain 1	myosin light chain 3
Image
GO Annotations	Cellular Component	Extracellular Region Cell Nucleus Cytoplasm Cytosol Intracellular Ferritin Complex Autolysosome Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Cytosol Muscle Myosin Complex Sarcomere A Band I Band
	Molecular Function	Ferroxidase Activity Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding	Actin Monomer Binding Calcium Ion Binding Structural Constituent Of Muscle Myosin II Heavy Chain Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Immune Response Negative Regulation Of Cell Proliferation Neutrophil Degranulation Negative Regulation Of Fibroblast Proliferation Oxidation-reduction Process	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Muscle Filament Sliding Positive Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	Striated Muscle Contraction
Drugs		Iron Dextran Iron
Diseases			Hypertrophic cardiomyopathy (HCM)
GWAS		Estradiol levels ( 22675492) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)	Metabolite levels ( 23823483) Microalbuminuria ( 26631737 31511532) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		35 interacting genes: BRD7 CD99 CDC16 CDC25A CRMP1 CSF3R CSNK2B DAXX ELL3 FTL FXR2 GOLM1 GRB2 KPNA2 LBP MAX MYL3 NR1I3 NR3C1 NR5A2 NTAQ1 PACSIN1 PCBP1 PCBP2 PIAS4 SDCBP SIRPA SOX5 SPP1 STAT1 TICAM2 TOLLIP TRAF4 UBR1 YWHAE	4 interacting genes: ATG101 CASP3 FTH1 UBC
Entrez ID		2495	4634
HPRD ID		00615	01183
Ensembl ID		ENSG00000167996	ENSG00000160808
Uniprot IDs		A0A024R525 P02794	A0A024R2Q5 P08590
PDB IDs		1FHA 2CEI 2CHI 2CIH 2CLU 2CN6 2CN7 2FHA 2IU2 2Z6M 3AJO 3AJP 3AJQ 3ERZ 3ES3 4DYX 4DYY 4DYZ 4DZ0 4OYN 4Y08 4YKH 4ZJK 5CMQ 5CMR 5GN8 5GOU 5JKK 5JKL 5JKM 5N26 5N27 5UP7 5UP8 5UP9 5VTD 5XB1 5YI5 5ZND 6B8F 6B8G 6FTV 6GSR 6H5I 6H6T 6H6U 6IPC 6IPO 6IPP 6IPQ 6J4A 6J7G 6KE2 6KE4	5TBY
Enriched GO Terms of Interacting Partners?
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