NR5A2 and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 19692572)
13

Data Source:
BioGRID (pull down)

		NR5A2	RAD54L2
Description		nuclear receptor subfamily 5 group A member 2	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Phospholipid Binding Zinc Ion Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Bile Acid Metabolic Process Hormone-mediated Signaling Pathway Embryo Development Ending In Birth Or Egg Hatching Tissue Development Intracellular Receptor Signaling Pathway Epithelial Cell Differentiation Regulation Of Cell Proliferation Homeostatic Process Cholesterol Homeostasis Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Viral Genome Replication Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Pancreas Morphogenesis Calcineurin-mediated Signaling Cellular Response To Leukemia Inhibitory Factor	DNA Duplex Unwinding
Pathways		Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Cerebrospinal T-tau levels ( 28247064) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010) Hepcidin/transferrin saturation ratio ( 27846281) Hyperinsulinemia in obesity ( 30327367) Hyperinsulinemia x BMI interaction ( 30327367) Inflammatory bowel disease ( 28067908) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Length of menstrual cycle ( 30202859) Lung adenocarcinoma ( 28604730) Lung function (FVC) ( 30061609 30804560) Menarche (age at onset) ( 25231870) Myopia ( 27182965) Nicotine dependence ( 28440896) Non-alcoholic fatty liver disease activity score ( 31311600) Pancreatic cancer ( 29422604 20101243 27579533 26098869 25086665) Rheumatoid arthritis ( 25014791) Ulcerative colitis ( 28067908) Uric acid levels ( 21294900) Urinary albumin excretion ( 30220432)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		19 interacting genes: ALB BCKDK DDB2 EDF1 FTH1 NCOA1 NCOA3 NPPA NR0B2 NR1I2 NRIP1 NSD1 PNRC1 PNRC2 POLR2D PROX1 RAD54L2 SMARCD3 UBE2I	20 interacting genes: AR ATN1 ATXN1 ATXN1L CNOT7 IMPDH2 NR3C1 NR5A1 NR5A2 PIAS1 PPARG PSMA3 RBPMS RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 UBE2I
Entrez ID		2494	23132
HPRD ID		06830	10018
Ensembl ID		ENSG00000116833	ENSG00000164080
Uniprot IDs		F1D8R9 O00482	B3KV54 Q9Y4B4
PDB IDs		1YOK 1YUC 1ZDU 2A66 3PLZ 3TX7 4DOR 4DOS 4IS8 4ONI 4PLD 4PLE 4RWV 5L0M 5L11 5SYZ 5UNJ 6OQX 6OQY 6OR1
Enriched GO Terms of Interacting Partners?
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