VGLL2 and TEAD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VGLL2	TEAD3
Description		vestigial like family member 2	TEA domain transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Protein C-terminus Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Skeletal Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Asymmetric Neuroblast Division
Pathways			YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS		Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Facial emotion recognition (fearful faces) ( 28608620) Height ( 20881960 31562340) Lung cancer ( 28604730) Night sleep phenotypes ( 27126917) Serum total protein level ( 29403010) Waist-hip ratio ( 28552196)	Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Offspring birth weight ( 31043758)
Interacting Genes		3 interacting genes: MEF2C TEAD1 TEAD3	13 interacting genes: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1
Entrez ID		245806	7005
HPRD ID		18282	04411
Ensembl ID		ENSG00000170162	ENSG00000007866
Uniprot IDs		Q8N8G2	Q99594
PDB IDs			5EMW
Enriched GO Terms of Interacting Partners?
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