GSPT2 and ETF1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		GSPT2	ETF1
Description		G1 to S phase transition 2	eukaryotic translation termination factor 1
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GO Annotations	Cellular Component	Cytosol Translation Release Factor Complex	Nucleus Cytoplasm Cytosol Translation Release Factor Complex
	Molecular Function	RNA Binding Translation Release Factor Activity GTPase Activity Protein Binding GTP Binding	RNA Binding Translation Release Factor Activity Protein Binding Translation Termination Factor Activity Translation Release Factor Activity, Codon Specific Ribosome Binding Sequence-specific MRNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translational Termination Translation Cell Cycle	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translational Termination Translational Termination Regulation Of Translational Termination Protein Methylation
Pathways		Eukaryotic Translation Termination Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Eukaryotic Translation Termination Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28552196) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		4 interacting genes: APP ETF1 GSPT1 PABPC1	5 interacting genes: GSPT1 GSPT2 KEAP1 LIG4 PPP2CA
Entrez ID		23708	2107
HPRD ID		02334	02616
Ensembl ID		ENSG00000189369	ENSG00000120705
Uniprot IDs		Q8IYD1	B7Z7P8 P62495
PDB IDs		3KUJ	1DT9 2HST 2KTU 2KTV 2LGT 2LLX 2MQ6 2MQ9 3E1Y 3J5Y 3JAG 3JAH 3JAI 4D5N 4D61 5A8L 5LZT 5LZU 5LZV 6D90 6IP8
Enriched GO Terms of Interacting Partners?
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