PRKD3 and DLAT

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PRKD3	DLAT
Description		protein kinase D3	dihydrolipoamide S-acetyltransferase
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Membrane	Mitochondrion Mitochondrial Matrix Mitochondrial Pyruvate Dehydrogenase Complex Pyruvate Dehydrogenase Complex
	Molecular Function	Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	Dihydrolipoyllysine-residue Acetyltransferase Activity Protein Binding Pyruvate Dehydrogenase (NAD+) Activity Identical Protein Binding
	Biological Process	Protein Phosphorylation Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Sphingolipid Biosynthetic Process Protein Kinase D Signaling	Glucose Metabolic Process Acetyl-CoA Biosynthetic Process From Pyruvate Pyruvate Metabolic Process Tricarboxylic Acid Cycle Sleep
Pathways		Sphingolipid de novo biosynthesis	Regulation of pyruvate dehydrogenase (PDH) complex Glyoxylate metabolism and glycine degradation Signaling by Retinoic Acid Pyruvate metabolism
Drugs			NADH Radicicol Dihydrolipoic Acid
Diseases			Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS		Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 24292274) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Schizophrenia ( 23974872) Systolic blood pressure ( 28135244 27841878)
Interacting Genes		9 interacting genes: BCL6 DLAT GSK3A IKBKG KPNA2 KPNB1 NUDT3 SKA2 VAMP2	7 interacting genes: PDHA1 PDHX PDK1 PDK2 PDK3 PDK4 PRKD3
Entrez ID		23683	1737
HPRD ID		06151	10578
Ensembl ID		ENSG00000115825	ENSG00000150768
Uniprot IDs		O94806	P10515 Q86YI5
PDB IDs		2D9Z	1FYC 1Y8N 1Y8O 1Y8P 2DNE 2PNR 2Q8I 3B8K 3CRK 3CRL 6CT0 6H55
Enriched GO Terms of Interacting Partners?
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