SLC7A11 and BAAT

Number of citations of the paper that reports this interaction (PubMedID 12763038)
7

Data Source:
HPRD (in vitro)

		SLC7A11	BAAT
Description		solute carrier family 7 member 11	bile acid-CoA:amino acid N-acyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Apical Part Of Cell Astrocyte Projection	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity	Protein Binding Palmitoyl-CoA Hydrolase Activity N-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Choloyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Acyl-CoA Hydrolase Activity Long-chain Acyl-CoA Hydrolase Activity Very Long Chain Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Amino Acid Transmembrane Transport Glutathione Metabolic Process Amino Acid Transport Visual Learning Response To Toxic Substance Response To Organic Cyclic Compound Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Response To Nicotine Regulation Of Cell Proliferation Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Leukocyte Migration Regulation Of Protein Transport Response To Redox State Limb Development Lens Fiber Cell Differentiation Platelet Aggregation Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Dipeptide Import Across Plasma Membrane Regulation Of Cysteine Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Protein Targeting To Peroxisome Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration
Pathways		Basigin interactions Amino acid transport across the plasma membrane	Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import
Drugs		Cystine Glutamic Acid Riluzole Sulfasalazine Acetylcysteine	Glycine
Diseases			Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS		Mood instability ( 31168069) Neurociticism ( 29500382)
Interacting Genes		4 interacting genes: BAAT OTUB1 SLC3A2 TERT	5 interacting genes: GOLGA8DP GOLGA8EP GOLGA8F PEX5 SLC7A11
Entrez ID		23657	570
HPRD ID		09720	08376
Ensembl ID		ENSG00000151012	ENSG00000136881
Uniprot IDs		Q9UPY5	Q14032
PDB IDs
Enriched GO Terms of Interacting Partners?
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