ARFIP2 and ITGB3BP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		ARFIP2	ITGB3BP
Description		ADP ribosylation factor interacting protein 2	integrin subunit beta 3 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Identical Protein Binding Cadherin Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity	Protein Binding Protein C-terminus Binding
	Biological Process	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division
Pathways		Retrograde transport at the Trans-Golgi-Network	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1	22 interacting genes: ACTN2 APP ARFIP2 CCNA2 CERT1 DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 LRRK2 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7
Entrez ID		23647	23421
HPRD ID		07209	09267
Ensembl ID		ENSG00000132254	ENSG00000142856
Uniprot IDs		A0A087X1E4 B4DUZ3 B4DXH2 P53365	D3DQ59 Q13352
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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