FPR2 and ERC1

		FPR2	ERC1
Description		formyl peptide receptor 2	ELKS/RAB6-interacting/CAST family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Cell Junction Ciliary Basal Body Presynaptic Membrane Synapse
	Molecular Function	Amyloid-beta Binding Complement Receptor Activity G Protein-coupled Receptor Activity N-formyl Peptide Receptor Activity Scavenger Receptor Binding Signaling Receptor Activity Cargo Receptor Activity	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding Cadherin Binding
	Biological Process	Microglial Cell Activation Positive Regulation Of Protein Phosphorylation Complement Receptor Mediated Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Receptor-mediated Endocytosis Chemotaxis Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Positive Regulation Of Superoxide Anion Generation Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Innate Immune Response Astrocyte Activation Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Chemotaxis Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis Cellular Response To Amyloid-beta	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Neutrophil degranulation
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Multiple sclerosis ( 31604244 24076602) Tourette syndrome ( 30818990)	Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420)
Interacting Genes		2 interacting genes: CAMP ERC1	19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		2358	23085
HPRD ID		00647	06181
Ensembl ID		ENSG00000171049	ENSG00000082805
Uniprot IDs		A0A024R4P3 P25090	G8JLD3 Q8IUD2 X6RLX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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