RBFOX2 and CLASP2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		RBFOX2	CLASP2
Description		RNA binding fox-1 homolog 2	cytoplasmic linker associated protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Kinetochore Condensed Chromosome Kinetochore Cell Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Ruffle Membrane Basal Cortex Mitotic Spindle
	Molecular Function	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding	Dystroglycan Binding Protein Binding Microtubule Binding Microtubule Plus-end Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance	Microtubule Cytoskeleton Organization Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Positive Regulation Of Exocytosis Cell Division Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways		FGFR2 alternative splicing	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Role of ABL in ROBO-SLIT signaling RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Metabolite levels ( 23823483)
Interacting Genes		53 interacting genes: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A CLASP2 DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 PCBP1 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC SPOP TOLLIP U2AF2 VAC14 ZNF137P	11 interacting genes: AKT1 CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2 MARK3 RBFOX2 SRPK2
Entrez ID		23543	23122
HPRD ID		15231	12054
Ensembl ID		ENSG00000100320	ENSG00000163539
Uniprot IDs		O43251	E3W994 E7ERI8 E7EW49 O75122
PDB IDs		2CQ3	3WOY 5NR4
Enriched GO Terms of Interacting Partners?
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