MAPK8IP2 and VPS33B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	VPS33B
Description		mitogen-activated protein kinase 8 interacting protein 2	VPS33B late endosome and lysosome associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Protein-containing Complex Neuronal Cell Body	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Clathrin-coated Vesicle HOPS Complex Platelet Alpha Granule Early Endosome Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Amyloid-beta Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein-containing Complex Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Behavioral Fear Response Receptor-mediated Endocytosis Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Signaling Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Endocytosis Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Excitatory Postsynaptic Potential Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of NMDA Receptor Activity Regulation Of AMPA Receptor Activity Negative Regulation Of Apoptotic Signaling Pathway	Vesicle Docking Involved In Exocytosis Endosome Organization Endosome To Lysosome Transport Protein Transport Vesicle-mediated Transport Peptidyl-lysine Hydroxylation Melanosome Localization Lysosome Localization Collagen Metabolic Process Membrane Fusion Platelet Alpha Granule Organization Autophagosome Maturation
Pathways			Prevention of phagosomal-lysosomal fusion
Drugs
Diseases			Arthrogryposis, renal dysfunction, and cholestasis; ARC syndrome
GWAS		Hip circumference ( 28552196)	Feeling hurt ( 29500382)
Interacting Genes		84 interacting genes: ADRB2 AFG3L2 ANAPC10 APP ASRGL1 BBS10 C1QTNF3 C22orf39 C8orf33 CFL1 CHN1 CRMP1 CRP CTNNBL1 DUSP16 DUSP18 EGFR ERBB2 ERG28 EZH2 FGF12 FGF13 FSCN1 GALNT3 GBP2 HLA-C IGIP ING4 ITSN1 KIFC2 KLC1 LEFTY2 LRP1 LRP2 LRP8 LSM8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 MNDA MRE11 MSRB3 NDUFS6 NUMB PLXNA3 PRSS23 RAI1 RBM4 RBX1 RPS6KB2 RYBP SCLT1 SH2D1B SLC39A13 SLPI SMARCB1 SMS SPINK2 SPSB3 SRP19 SYNE2 TARBP2 TIAM1 TMEM128 TP53BP2 UNC119 USP46 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF670 ZNF784 ZNRD1	6 interacting genes: APP MAP3K20 MAPK8IP2 TNIP1 UVRAG VIPAS39
Entrez ID		23542	26276
HPRD ID		09674	10541
Ensembl ID		ENSG00000008735	ENSG00000184056
Uniprot IDs		Q13387	A0A0S2Z577 B7Z1N4 F5H008 Q9H267
PDB IDs
Enriched GO Terms of Interacting Partners?
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