SRRM2 and PRPF6

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SRRM2	PRPF6
Description		serine/arginine repetitive matrix 2	pre-mRNA processing factor 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cajal Body Nuclear Speck U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Height ( 31562340)	Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732)
Interacting Genes		14 interacting genes: APP CLK1 CSNK2A1 PIN1 PNN PRPF6 SNIP1 SRPK2 SRRM1 SRSF4 TTC14 XRN1 YWHAB YWHAG	11 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 TIMM44 TXNL4B YWHAB
Entrez ID		23524	24148
HPRD ID		06913	10729
Ensembl ID		ENSG00000167978	ENSG00000101161
Uniprot IDs		A0A140VK53 Q9UQ35	O94906
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6QDV	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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