SCRIB and TJP2

Number of citations of the paper that reports this interaction (PubMedID 15975580)
26

Data Source:
HPRD (in vivo, in vitro)

		SCRIB	TJP2
Description		scribble planar cell polarity protein	tight junction protein 2
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GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Cell-cell Junction Adherens Junction Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Lamellipodium Cell Junction Cell Leading Edge Scrib-APC-beta-catenin Complex Myelin Sheath Abaxonal Region Presynaptic Membrane Cell-cell Contact Zone Synapse Postsynaptic Membrane Extracellular Exosome Synaptic Membrane Glutamatergic Synapse Extrinsic Component Of Postsynaptic Density Membrane	Nucleus Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Cell-cell Contact Zone
	Molecular Function	Protein Binding Cadherin Binding	Guanylate Kinase Activity Protein Binding Protein Domain Specific Binding Protein Binding, Bridging Cadherin Binding Protein Tyrosine Kinase Binding
	Biological Process	Neural Tube Closure Positive Regulation Of Receptor Recycling Cell Proliferation Embryo Development Synaptic Vesicle Targeting Cell Migration Cochlear Nucleus Development Evasion Or Tolerance By Virus Of Host Immune Response Establishment Of Apical/basal Cell Polarity Post-anal Tail Morphogenesis Suppression By Virus Of Host STAT1 Activity Suppression By Virus Of Host STAT2 Activity Wound Healing Positive Regulation Of Apoptotic Process Receptor Clustering Astrocyte Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Mitotic Cell Cycle Synaptic Vesicle Endocytosis Positive Chemotaxis Auditory Receptor Cell Stereocilium Organization Apoptotic Process Involved In Morphogenesis Mammary Gland Duct Morphogenesis Protein Localization To Adherens Junction Activation Of GTPase Activity Receptor Localization To Synapse Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Homotypic Cell-cell Adhesion Hippo Signaling GMP Metabolic Process GDP Metabolic Process Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Positive Regulation Of Maintenance Of Permeability Of Blood-brain Barrier
Pathways		Asymmetric localization of PCP proteins	Signaling by Hippo Apoptotic cleavage of cell adhesion proteins
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870)	Macular thickness ( 30535121) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Refractive error ( 23396134) Renal sinus fat ( 22044751) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		11 interacting genes: APC ARHGEF7 EXOSC10 LPP MAPK3 PRKCA STX4 TJP2 TRIP6 TSHR UBE3A	17 interacting genes: CDK6 CGN CLDN1 CLDN2 CLK1 CTNNA1 EPB41 HGS HSPB1 SAFB SCRIB SH3KBP1 SRPK2 TJP1 YWHAB YWHAG YWHAZ
Entrez ID		23513	9414
HPRD ID		06984	06369
Ensembl ID		ENSG00000180900	ENSG00000119139
Uniprot IDs		A0A0G2JNZ2 A0A0G2JPP5 A0PJK8 Q14160	B7Z2R3 B7Z954 Q9UDY2
PDB IDs		1UJU 1WHA 1X5Q 2W4F 4WYT 4WYU 5VWC 5VWI 5VWK 6EEY 6ESP 6MS1 6MTU 6MTV 6MYE 6MYF	2OSG 3E17
Enriched GO Terms of Interacting Partners?
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