FOLR1 and NCAPH2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		FOLR1	NCAPH2
Description		folate receptor alpha	non-SMC condensin II complex subunit H2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Endosome Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface ER To Golgi Transport Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Membrane Cell Junction Intercellular Bridge
	Molecular Function	Folic Acid Binding Drug Binding Signaling Receptor Activity Methotrexate Binding Folic Acid Receptor Activity	Chromatin Binding Protein Binding
	Biological Process	Heart Looping Neural Crest Cell Migration Involved In Heart Formation Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis ER To Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Folic Acid Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Axon Regeneration Folic Acid Metabolic Process COPII Vesicle Coating Regulation Of Canonical Wnt Signaling Pathway Pharyngeal Arch Artery Morphogenesis Anterior Neural Tube Closure Cellular Response To Folic Acid Folate Import Across Plasma Membrane	Mitotic Chromosome Condensation Meiotic Chromosome Condensation T Cell Differentiation In Thymus Chromosome Organization Mitotic Sister Chromatid Separation Female Meiosis Chromosome Separation
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport	Condensation of Prophase Chromosomes
Drugs		Folic Acid Vintafolide Farletuzumab
Diseases
GWAS			B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cerebrospinal fluid clusterin levels ( 26545630) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 20139978) Red blood cell traits ( 23222517)
Interacting Genes		5 interacting genes: CUL3 INTS4 IRAK3 LYN NCAPH2	11 interacting genes: ACTN2 EGLN3 FOLR1 LMO2 PRPF31 SNRPC TRAF2 TTC25 TTC32 TUBB USHBP1
Entrez ID		2348	29781
HPRD ID		00638	11783
Ensembl ID		ENSG00000110195	ENSG00000025770
Uniprot IDs		A0A024R5H1 P15328	Q6IBW4
PDB IDs		4KM6 4KM7 4KMX 4LRH 5IZQ
Enriched GO Terms of Interacting Partners?
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